COURSE OVERVIEW:

The meaning of this course lies in the technical mastery of the sophisticated hardware and software systems that drive contemporary chemical and physical analysis. In an age of high-throughput data, the "Modern Instrumental" analyst must understand not just the "How" but the "Why" behind the interaction of energy and matter. This program provides the engineering and scientific expertise required to operate, optimize, and troubleshoot high-end analytical platforms, ensuring that the laboratory remains at the cutting edge of precision and speed.

The scope of the training focuses on the primary families of instrumental analysis: Chromatography, Spectroscopy, and Mass Spectrometry. It addresses the advanced principles of High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Inductively Coupled Plasma (ICP), and the various interfaces of Mass Spectrometry (LC-MS and GC-MS). Participants will explore the mechanics of "Hyphenated Techniques" and the role of automated sample preparation in reducing human error and increasing analytical sensitivity.

The coverage includes a deep investigation into detector physics, column chemistry, and the digital processing of analytical signals. The course emphasizes the importance of "Instrument Qualification" (IQ/OQ/PQ) and the interpretation of complex spectra for qualitative and quantitative identification. By mastering these instrumental protocols, participants will be able to maximize instrument uptime, enhance the "Limit of Detection" for trace analysis, and deliver high-fidelity data that supports critical research and industrial processes.

COURSE OBJECTIVES:

After completion of this course, the participants will be able to:

• Define the core principles of electromagnetic radiation and matter interaction.
• Master the mechanics of High-Performance Liquid Chromatography (HPLC).
• Optimize Gas Chromatography (GC) parameters for complex separations.
• Interpret Mass Spectrometry (MS) fragmentation patterns for identification.
• Utilize ICP-OES and ICP-MS for trace elemental analysis.
• Configure and troubleshoot "Hyphenated" systems (LC-MS and GC-MS).
• Execute Instrument Qualification (IQ, OQ, and PQ) protocols.
• Select the appropriate detector for specific analytical challenges.
• Optimize "Sample Introduction" systems for various matrices.
• Interpret "Signal-to-Noise" ratios to improve analytical sensitivity.
• Manage the preventive maintenance schedule for advanced hardware.
• Validate instrumental methods according to international standards.

TARGET AUDIENCE:

This course is intended for Analytical Chemists, Instrumental Specialists, Laboratory Scientists, and Technical Managers in pharmaceutical, environmental, and industrial labs.

TRAINING COURSE METHODOLOGY:

A highly interactive combination of lectures, discussion sessions, and case studies will be employed to maximize the transfer of information, knowledge, and experience. The course will be intensive, practical, and highly interactive. The sessions will start by raising the most relevant questions and motivating everybody to find the right answers. The attendants will also be encouraged to raise more of their questions and to share in developing the right answers using their analysis and experience. There will also be some indoor experiential activities to enhance the learning experience. Course material will be provided in PowerPoint, with necessary animations, learning videos, and general discussions.

The course participants shall be evaluated before, during, and at the end of the course.

COURSE CERTIFICATE:

National Consultant Centre for Training LLC (NCC) will issue an Attendance Certificate to all participants completing a minimum of 80% of the total attendance time requirement.