COURSE OVERVIEW:

The meaning of this course lies in the transition from a routine GC operator to an "Expert" user capable of managing high-complexity systems and solving the most difficult analytical puzzles. In a high-throughput lab, the ability to recognize subtle data artifacts and diagnose their physical cause is essential for data integrity. This program provides the deep technical "intuition" and systematic diagnostic procedures required to keep advanced GC systems operating at peak performance.

The scope of the training focuses on the advanced operation of specialized GC configurations, including multi-detector systems, gas sampling valves, and hyphenated techniques like GC-MS and GC-FTIR. It addresses the "Troubleshooting Tree" approach, teaching participants how to isolate problems in the gas supply, electronics, chemistry, or software. Participants will explore the use of "Advanced Diagnostics" to evaluate column health and detector sensitivity beyond the basic manufacturer tests.

The coverage includes detailed instruction on the interpretation of "Strange Chromatograms," the management of "Matrix Effects," and the recovery of systems after a major "Contamination Event." The course emphasizes the expert-level maintenance of the ion source, the optimization of complex temperature programs, and the configuration of advanced data processing algorithms. By mastering these expert skills, participants will be able to lead their laboratory teams through difficult analytical challenges and ensure the highest confidence in every GC result.

COURSE OBJECTIVES:

After completion of this course, the participants will be able to:

• Operate high-complexity GC systems with multiple inlets and detectors.
• Apply a systematic "Diagnostic Tree" for rapid troubleshooting.
• Identify the physical cause of "Retention Time Drifts" and "Baseline Spikes."
• Recover GC systems after major "Oil" or "Matrix" contamination.
• Optimize "SIM" and "MRM" transitions in advanced GC-MS/MS.
• Troubleshoot "Communication" and "Software Integration" failures.
• Evaluate the "Resolving Power" and "Efficiency" of old versus new columns.
• Manage "Gas Sampling Valves" and "Multi-Port" switching systems.
• Diagnose "Carrier Gas Contamination" using spectral signatures.
• Perform expert-level "Source Tuning" and "Calibration" for MS.
• Interpret "Isotope Ratios" and "Fragmentation Patterns" for confirmation.
• Lead a team in the "Emergency Restoration" of critical GC services.

TARGET AUDIENCE:

This course is intended for Expert Analysts, Lab Section Heads, GC System Owners, and Senior Researchers who manage complex chromatography assets.

TRAINING COURSE METHODOLOGY:

A highly interactive combination of lectures, discussion sessions, and case studies will be employed to maximize the transfer of information, knowledge, and experience. The course will be intensive, practical, and highly interactive. The sessions will start by raising the most relevant questions and motivating everybody to find the right answers. The attendants will also be encouraged to raise more of their questions and to share in developing the right answers using their analysis and experience. There will also be some indoor experiential activities to enhance the learning experience. Course material will be provided in PowerPoint, with necessary animations, learning videos, and general discussions.

The course participants shall be evaluated before, during, and at the end of the course.

COURSE CERTIFICATE:

National Consultant Centre for Training LLC (NCC) will issue an Attendance Certificate to all participants completing a minimum of 80% of the total attendance time requirement.